Obesity is thought to be a disease of inflammation, according to Michael Glade, Ph.D.
I became acquainted with his work through a DVD given to me by NeuroScience. We have use NeuroScience protocols with great success; a company that focuses on “Target Amino Acids” as a means to address healing of the adrenal gland and balance neurotransmitters for the treatment of many symptoms including anxiety, sleep maintenance and insomnia, depression, and memory loss.
Dr. Glade is a Certified Nutritional Specialist (CNS) with degrees from the Massachusetts Institute of Technology (MIT) and Cornell University and teaching and research experience at Rutgers University, the University of Maryland, Northwestern University and at the Nutrition Institute of the University of Bridgeport. 
Dr. Glade contends that when a patient has obesity for 5 years or more, the cellular mechanism is disrupted and regulation is thrown off through nutritional and other influences. Cancer, arthritis, allergy, digestive literature look for a common thread which is traditionally separate in peoples minds as separate diseases, but it is looking more and more that they are individual symptoms manifested in an individual similarly condition. It starts with people who eat improperly and once the condition of unregulated inflammation develops, then under that umbrella, one could end up with all the listed above common disease.
Insulin resistance falls under this umbrella where something goes arye in the metabolism of glucose within muscle cells. People don’t get better, they get worse. It doesn’t cure or arrest with the use of any existing medications. Control of diabetes II and insulin is not cured or suppressed by any existing treatment medications. The premise is that people who have insulin resistance will slowly but surely deteriorate. Dr. Glade believes there is something missing in that model. We are treating a blood level of insulin but not the disease. He suggests that something, possibly environmental is the missing piece.
Research suggest abdominal fat in the visceral organ (around organs inside) appears to be genetically different from much of the than other fat in the body. It is the most insulin responsive part of the body. In insulin resistance patients, the insulin is not responsive on the muscle whereas the belly fat stores is over reactive and sucks the insulin up. The degree of hypersensitive reflects as the more inflamed they become. The more inflamed they are the more tendencies they have to over-store abdominal fat.
Insulin control in the pancreas is disturbed when the body is carrying a high amount of an inflammatory formed, abnormal cytokine molecules produced by the body so one part of the body can communicate with another part. Overreactions throughout the body because of lifestyle, environment, diet, result in tissue not normally responsive, but will then activate due to an overexposure of inflammation. This will force the organ to over-respond. This condition is not well monitored or regulated in the body. The blood has an almost unlimited capacity to carry these inflammatory molecules in the body. This response is what needs to be brought under control and can only be accomplished by improved lifestyle, environmental factors, detoxification, and a healthy diet.
Part 2 will address what can be done about this dynamic problem.
Dr. Michael Glade emphasizes specific dietary plans and supplement protocols, especially in programs targeted at brain function, weight reduction, smoking cessation, and life extension for the terminally ill. Dr. Glade lectures extensively across the US and Europe. Dr. Glade is a noted researcher who is deeply appreciated in the nutritional and scientific communities for providing a significant body of peer-reviewed substantiation for multiple health claims that have been approved by the FDA.